Q&A Forum > > Reply To: Substituting a CAT-6A Ethernet Patch Cable, for a CAT-5E Patch Cable Start a new discussion December 21, 2020 at 11:21 am #46571 TeamKomando:JohnParticipant @264458 Hello leftblank15, You sure can, however if you were using a 10GB network (I’m sure you are not) you would notice. Cat5e / Cat6 are interchangeable.